Metabolite analysis

By definition, metabolites are small intermediary molecules that arise from intricate biochemical pathways. They play a crucial role in cell signaling, regulation of cellular functions, and energy production. During the manufacturing of biologics, the analysis of metabolites will gain useful insights into optimal cell culture conditions like nutrient values, oxygen supply and metabolic state, to improve cell growth, productivity and quality of the manufacturing process.

Besides a real-time assessment of the cell growth of the batch, the analysis of metabolites also give valuable information on process related impurities like microbiological contaminants.

At Biofidus we offer standardized chromatographic assays for a broad range of metabolites like amino acids, organic acids, polyamines, surfactants, sugars, fatty acids, vitamins, nucleotides, secondary messengers and process related impurities. 

In accordance with your needs, we adapt and, if required, qualify our platform methods tailored to your distinct analytical question.

Get in contact with our expert to find the optimal strategy for your project and to speak directly from scientist to scientist.